Treatment Pain and Inflammation in Osteoarthritis, Rheumatoid Arthritis, Acute Gout and Ankylosing Spondylitis {Etoricoxib}

 Contraindication:

                    Patients with known hypersensitivity to Etoricoxib or to any of the excipients of this medicinal product, active peptic ulceration or gastro-intestinal bleeding, severe hepatic dysfunction, children under 16 years of age, inflammatory bowel disease, uncontrolled hypertension, breast feeding.

Indication:

Pain and Inflammation in Osteoarthritis, Rheumatoid Arthritis, Acute Gout and Ankylosing Spondylitis.

 

Dosage and Administration:

· Osteoarthritis, ADULT and CHILD over 16 years, 30 mg once daily, increased if necessary to 60 mg

once daily.

· Rheumatoid arthritis and ankylosing spondylitis, ADULT and CHILD over 16 years, 90 mg once daily.

· Acute gout, ADULT and CHILD over 16 years, 120 mg once daily for max. 8 days.

Precaution:

Decreased kidney function and liver function, dehydration, hypertension, history of heart failure,

perforation and people over 65 years of age.

Side Effect:

Dizziness, headache, gastro-intestinal disorders ( e.g. abdominal pain, flatulence, heart burn), palpitation,

fatigue, influenza-like symptoms, ecchymosis; less commonly dry mouth, taste disturbance, mouth ulcer,

appetite and weight change, atrial fibrillation, transient ischaemic attack, chest pain, flushing, cough,

dyspnoea, epistaxis, anxiety, mental acuity impaired, paraesthesia, electrolyte disturbance, myalgia and

arthralgia; very rarely confusion and hallucinations.

Drug Interaction:

Warfarin, ACE Inhibitor, Rifampicin, Lithium, Birth control pills, Methotrexate, Digoxin.

Use in Pregnancy and Lactation:

Not recommended.