Bromhexine
HCl is highly effective mucolytic expectorant.
Indication:
Bromhexine
HCl is indicated in the treatment of respiratory disorders associated with
productive cough. These include; tracheobronchitis, bronchitic with emphysema,
bronchiectasis,
bronchitis with bronchospasm, chronic inflammatory pulmonary conditions and pneumoconiosis.
Dosage
and administration:
Adults:
The recommended daily dose is 2 to 4 teaspoonful 3 tines daily. Initially 4
teaspoonful 3 times daily and then as required.
Children:
Suggested dosage for children under 2 years is ¼ teaspoonful 3 times daily, for
2-5 years ½ teaspoonful 3 times daily and for children aged 5-10 years 1
teaspoonful 3 times daily.
Precaution:
Mucolytics
may disrupt the gastric mucosa so bromhexine should be used with care in
patients with a history of peptic ulceration. Care is also advisable in
asthmatic patients.
Contraindication:
Bromhexine
is contraindicated for use in patients with known hypersensitivity to
bromhexine hydrochloride (or any of the other ingredients in the product).
Side
effect:
Gastrointestinal
side effects may occur occasionally with Bromhexine and a transient rise in serum
aminotransferase values has been reported. Other reported adverse effects
include headache, dizziness, sweating and skin rash.
Use
in pregnancy and lactation:
Category
B: Bromhexine has been taken by a large number of pregnant women and women of child
bearing age without any proven increase in the frequency of malformations or
other direct or indirect harmful effects on the fetus having been observed.
It is not known whether Bromhexine is excreted in
breast milk or whether it has a harmful effect on the breastfeeding infant.
Therefore it is not recommended for breastfeeding mothers unless the potential
benefits to the patient are weighed against the possible risk to the infant
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